Spyros Mezitis, MD, PhD
Top Rated Endocrinologist in New York City
30+ years of experience
Comprehensive Services for Diabetes, Thyroid and Hormone Disorders, Weight Loss, Osteoporosis, Adrenal and Pituitary Disorders, PCOS, Anti-Aging

Professional Affiliations












Dr. Spyros Mezitis
Endocrinologist | Researcher | Your Health Partner
Dr.Mezitis brings over 30 years of clinical excellence in Endocrinology.
Currently Assistant Professor at New York-Presbyterian/Weill Cornell and Lenox Hill Hospital/Northwell Health.
He combines cutting-edge research with compassionate patient care.
Education & Credentials
Holistic Care
Personalized Plans
Tailored to your unique medical history and goals
Evidence-Based
Latest research and proven treatment protocols
Coordinated Care
Seamless collaboration with specialists
Lifestyle Focus
Nutrition and wellness integrated into treatment
Transform Your Health Journey
World-class endocrinology care tailored to your unique needs
Diabetes Excellence
Type 1, Type 2 & Gestational
Master your blood sugar with personalized treatment plans that go beyond numbers. Real-time glucose monitoring, insulin pump optimization, and 24/7 urgent care support—because your health doesn't wait.
Thyroid Optimization
Hypo/Hyperthyroidism & Cancer Care
Your thyroid controls everything—metabolism, energy, mood. Get expert diagnosis and treatment for the 12% of Americans living with thyroid conditions. Early intervention = exceptional outcomes.
Bone Health & Vitality
Osteoporosis & Vitamin D
Build strength from within. Cutting-edge treatments combined with nutrition and lifestyle strategies to keep your bones strong and your future fracture-free. Prevention is power.
Hormone Harmony
PCOS, Fertility, Testosterone & More
Restore balance, reclaim vitality. Expert care for PCOS, fertility challenges, testosterone optimization, and adrenal/pituitary disorders. Your path to optimal hormone health—and growing your family—starts here.
Medical Weight Loss
GLP-1 Therapy (Semaglutide, Tirzepatide)
Science-backed weight transformation with the latest GLP-1 medications. We provide:
- Personalized injection training & nutrition planning
- Precision dosing & side-effect management
- Goal-driven progress tracking with labs
Ready to Take Control of Your Health?
Schedule your personalized consultation with Dr. Mezitis and experience world-class endocrinology care
Office Hours
Monday - Friday
9:00 AM - 5:00 PM
Visit Us
220 E 69th StNew York, NY 10021