Spyros Mezitis, MD, PhD

Top Rated Endocrinologist in New York City

30+ years of experience

Comprehensive Services for Diabetes, Thyroid and Hormone Disorders, Weight Loss, Osteoporosis, Adrenal and Pituitary Disorders, PCOS, Anti-Aging

Dr. Spyros Mezitis

Professional Affiliations

Dr. Spyros Mezitis

Endocrinologist | Researcher | Your Health Partner

30+
Years Experience
PhD
Neuropathology
2
Top NYC Hospitals
100+
Published Studies

Dr.Mezitis brings over 30 years of clinical excellence in Endocrinology.

Currently Assistant Professor at New York-Presbyterian/Weill Cornell and Lenox Hill Hospital/Northwell Health.

He combines cutting-edge research with compassionate patient care.

Education & Credentials

1998-2026
Private Practice
Endocrinology Private Practice — New York City
1998
Fellowship
NY-Presbyterian / Weill Cornell, MSK, HSS — Endocrinology
1995
Residency
Thomas Jefferson University — Internal Medicine
1992
MD
Thomas Jefferson University Medical College
1987
PhD
University of Pennsylvania — Neuropathology/Cell Biology

Holistic Care

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Personalized Plans

Tailored to your unique medical history and goals

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Evidence-Based

Latest research and proven treatment protocols

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Coordinated Care

Seamless collaboration with specialists

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Lifestyle Focus

Nutrition and wellness integrated into treatment

Transform Your Health Journey

World-class endocrinology care tailored to your unique needs

Diabetes Excellence

Type 1, Type 2 & Gestational

Master your blood sugar with personalized treatment plans that go beyond numbers. Real-time glucose monitoring, insulin pump optimization, and 24/7 urgent care support—because your health doesn't wait.

Thyroid Optimization

Hypo/Hyperthyroidism & Cancer Care

Your thyroid controls everything—metabolism, energy, mood. Get expert diagnosis and treatment for the 12% of Americans living with thyroid conditions. Early intervention = exceptional outcomes.

Bone Health & Vitality

Osteoporosis & Vitamin D

Build strength from within. Cutting-edge treatments combined with nutrition and lifestyle strategies to keep your bones strong and your future fracture-free. Prevention is power.

Hormone Harmony

PCOS, Fertility, Testosterone & More

Restore balance, reclaim vitality. Expert care for PCOS, fertility challenges, testosterone optimization, and adrenal/pituitary disorders. Your path to optimal hormone health—and growing your family—starts here.

Medical Weight Loss

GLP-1 Therapy (Semaglutide, Tirzepatide)

Science-backed weight transformation with the latest GLP-1 medications. We provide:

  • Personalized injection training & nutrition planning
  • Precision dosing & side-effect management
  • Goal-driven progress tracking with labs
🎯 Your Health Transformation Starts Here

Ready to Take Control of Your Health?

Schedule your personalized consultation with Dr. Mezitis and experience world-class endocrinology care

Call (212) 288-6661
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Office Hours

Monday - Friday
9:00 AM - 5:00 PM